The Ph.D. study programme has the aim to expose students to the complexity of human physiology as well as selected disease states thereof. Finally, the postgraduate study programme should introduce and inspire the students to become familiar with tools and methods through which a conceptual holistic understanding of complex biological systems can be achieved by bringing experimental research together with concepts generated in theoretical informatics and informations science. Hereto, different scientific subject areas covering different aspects of regenerative medicine such as stem cell research, oncology and autoimmunity. Research projects form these areas that are studied initially in a traditionally reductionist manner shall be related with computational science support of the Shanghai Institute for Bioinformation Technologies to link experimental work with the world knowledge that is publicly available using most modern bioinformatic and systems biology approaches.
Figure: Outline of the teaching modules for the study programme of the IRTG .Computational Biology in Regenerative Medicine.. The study programme for each term contains four main teaching modules that comprise i) 1-day workshops (WS) with invited lectures, ii) 3-day scientific meetings / spring schools (SM) with active participation of the students and invited scientists, and iii) weekly seminars / lectures (two hours) during the term (seminar blocks (SB; 16 weeks)) to which iv) specific practicals (P; 1-week, full day) are associated to.
The teaching programme will be individualized to the needs of each student by complementing his/her pre-existing expert knowledge required to fulfill the objectives of the IRTG-Programme. To this purpose, the Research Programme (Prof. Thiesen) and the Study Programme (Prof. Glocker) has been highly connected by the supervision of each Ph.D. project with the Thesis Committee (Prof. Tiedge; see below) and experts in computational biology (Lübeck, Rostock, Greifswald, Shanghai). Both, scientific meetings (SM) and workshops (WS) shall be open for participation to Ph.D. students from the University of Rostock and to Ph.D. students from abroad (e.g. Denmark) that express an interest in the respective topics (see letters of intent in annex 12). These two teaching modules shall also be offered to research students e.g. from our partners in Lübeck and Greifswald. The applicants also expect, that associated PIs will make the IRTG study programme accessible to further Ph.D. students from their groups. The study programme modules will comprise up to a total of 98 teaching course hours per seminar block / term (6.1 SWS). Together with preparation and after processing (180 hours) by the students, who are assembled into study groups for each seminar block, and with attending the .thesis committee meetings., total work load for the study programme comprises 280 hours.
The general objectives of the postgraduate training programme will be achieved in close concordance with the individual needs/interest/achievements of the student. For the Ph.D. study programme students will be grouped into study groups. Each student will be encouraged to establish/form or to join study groups of 2 to 3 members that are obliged to select topics from a pool of subjects assigned to each seminar block (preliminary list of topics, see Attachment), matching with the respective seminar topics. The emphasis of the study programme will be determined by the topics of workshops scheduled for this term flanked by scientific meetings with international participants (invited speakers). According to the qualification of the Ph.D. students each study group should have at least mingled with one dry or wet lab expert. By having set the frame for supporting individual study activities, students are encouraged to assort an individual study plan taking into account individual preferences and skills complemented by competence offered due to the interdisciplinary nature of the Ph.D. research projects (see study and research programme). The communication platform for ensuring the close communication between Shanghai and Rostock and vice versa will be part of the LIMS database system called ProteoBase established at the Proteome Center Rostock. During the pre-implementation phase of this grant application the URL: www.IRTG-ComBio.de has been established to initially support the communication and finally the exchange of data between participants within the framework of the research programme executed in Rostock and Shanghai.